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The following is a brief outline of the process we will follow to examine the system requirements and build our database security profile. This process is iterative in that we can start with each group of requirements, examine it, move onto the next group of requirements, and revisit completed requirements for more refinement: Define or locate requirements documentation, such as use cases. Identify coarse-grained verb object assertions for the database security profile. Identify fine-grained database security profile to include actors and conditions. Establish DBV factors based on business or system conditions. Identify DBV realms and realm objects from objects. Identify accounts, roles, and DBV realm authorizations from actors. Establish DBV command rules from conditions. Establish DBV Secure Application Roles (SARs) from conditions.

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Acetyl-CoA metabolized through the TCA cycle yields 3 NADH, 1 FADH2, and 1 GTP a total of 12 ATP equivalents (3 from each NADH, 2 from each FADH2, and 1 GTP 12 in all). Four O s are used, 1 for each NADH and FADH2. The P in this case is 10 (12 2 for the activation of acetate to acetyl-CoA). The P/O 10/4 2.5. P/O ratios for anything else are calculated in the same way.

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1. We can use the property of common logarithms that converts a product into a sum: log10 xy = log10 x + log10 y In this case, x = 2.3713018568 and y = 0.902780337. If we use the calculator found in the Windows computer operating system: log10 (2.3713018568 0.902780337) = log10 2.3713018568 + log10 0.902780337 0.37498684137 + ( 0.0444179086) 0.37498684137 0.0444179086 0.3305689328 This is the common logarithm of the product we wish to find. If we find the common antilogarithm of this, we ll get the desired result. Inputting this to a calculator and then rounding to three decimal places: antilog10 (0.3305689328) 2.141

treatment is relatively benign, as cell viability and DNA replication are not affected at the energy levels used for suppressing procollagen production Optimizing treatment schedules and using relatively low energy densities might permanently suppress keloids, although data remains sparse Abergel and colleagues concluded that sequential treatment, using the CO2 laser to remove keloids followed by the Nd:YAG laser to suppress recurrence, may be an even more effective treatment Unfortunately, most of the data was qualitative, as percent improvements of the patients and histology were not published Patient success was described in only one case study27 For many years, keloids have been treated with ablative CO2 lasers with mixed results The CO2 laser emits a wavelength of 10 600 nm in the far infrared spectrum, and destroys tissue by vaporizing intracellular water It also photocoagulates blood vessels and seals small lymphatics and nerve endings virtually bloodlessly.

Unlike PDL treatment, the CO2 laser penetration depends only on the tissue s water content, making vascularity irrelevant, and the treatment less speci c and more prone to widespread tissue damage57 The original CW CO2 lasers caused extensive thermal damage with unacceptable aesthetic results58 However, it has since been redesigned as a superpulsed laser to deliver higher uences (often greater than 7 J/cm2) in much shorter pulse durations (1 ms) It is now possible to vaporize super cial tissue layers with a reduced area of thermal damage compared to what a CW CO2 laser would produce, although in practice this is generally achieved using a spot size of 08 mm or smaller59 It would seem the ideal laser to treat the undervascularized keloid.

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However, despite these redesigns, CO2 lasers still carry a high recurrence rate when treating keloids, and are currently not widely accepted for their treatment20 Also, because the intensity of postoperative erythema relates directly to the amount of thermal necrosis, CO2 lasers will cause more severe, prolonged erythema than other ablative lasers, such as the Er:YAG60 The evidence supporting CO2 laser use for keloids is sparse A 1984 study by Apfelberg and colleagues measured the effects of ablative lasers argon and CO2 lasers on 13 patients with well-established keloids Unfortunately, all except one earlobe keloid either recurred or showed no clinical improvement There was a minor temporary relief of pain and itching, but all symptoms returned to their original intensity over a period of weeks to months Researchers found no long-term bene cial effects with either treatment47.

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